Evaluation of Immunohistochemical Markers and Features of their Dynamics in Gum Biopsies in Various Stages of Periodontitis

Abstract

Periodontal disease "Periodontosis" is the gradual destruction of the periodontium that surrounds the tooth and holds it in the tooth cavity (alveoli). The periodontium includes the gingiva, periodontal ligament (connective tissue), alveolar bone, and root cementum. Diagnosis of true periodontal disease is complicated by the addition of periodontitis, an aggressive inflammatory process in periodontal tissues. Despite the similarity of the names, these are different dental pathologies, but they are similar in the manifestation of the consequences of timely treatment. In severe cases, the patient faces complete dysfunction of the teeth with the need to replace them with implants and prostheses.