Directed Bone Regeneration in Surgical Dentistry: Modern Approaches and Clinical Effectiveness

Abstract

Guided Bone Regeneration (GBR) is an advanced surgical approach widely used in contemporary dentistry to restore deficient alveolar bone structures, particularly in preparation for dental implantation. This study investigates the theoretical background, clinical application, material effectiveness, and psychosocial factors influencing GBR outcomes in the context of Uzbekistan. A total of 120 patients from urban and rural clinics participated in a six-month observational study involving resorbable and non-resorbable barrier membranes combined with osteoconductive biomaterials. Quantitative analysis using cone-beam computed tomography (CBCT) demonstrated significantly greater bone regeneration in patients treated with non-resorbable PTFE membranes compared to those with resorbable collagen membranes. In addition to structural outcomes, the study identifies the role of hygiene practices and psychological stability as critical determinants of successful GBR. The findings provide evidence for a multidisciplinary, patient-centered approach and contribute region-specific insights to the broader literature on regenerative oral surgery.